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Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Pore-forming toxins (PFT) are water-soluble proteins that possess the remarkable ability to self-assemble on the membrane of target cells, where they form pores causing cell damage. Here, we elucidate the mechanism of action of the haemolytic protein fragaceatoxin C (FraC), a α-barrel PFT, by determ...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nat Commun |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Pub. Group
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351601/ https://ncbi.nlm.nih.gov/pubmed/25716479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7337 |
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