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3D hotspots of recurrent retroviral insertions reveal long-range interactions with cancer genes
Genomically distal mutations can contribute to the deregulation of cancer genes by engaging in chromatin interactions. To study this, we overlay viral cancer-causing insertions obtained in a murine retroviral insertional mutagenesis screen with genome-wide chromatin conformation capture data. Here w...
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| Published in: | Nat Commun |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Pub. Group
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351571/ https://ncbi.nlm.nih.gov/pubmed/25721899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7381 |
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