Integration of gene expression and DNA-methylation profiles improves molecular subtype classification in acute myeloid leukemia

BACKGROUND: Acute Myeloid Leukemia (AML) is characterized by various cytogenetic and molecular abnormalities. Detection of these abnormalities is important in the risk-classification of patients but requires laborious experimentation. Various studies showed that gene expression profiles (GEP), and t...

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Bibliografische gegevens
Gepubliceerd in:BMC Bioinformatics
Hoofdauteurs: Taskesen, Erdogan, Babaei, Sepideh, Reinders, Marcel MJ, de Ridder, Jeroen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347619/
https://ncbi.nlm.nih.gov/pubmed/25734246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S4-S5
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