Efficient and Allele-Specific Genome Editing of Disease Loci in Human iPSCs

Efficient and precise genome editing is crucial for realizing the full research and therapeutic potential of human induced pluripotent stem cells (iPSCs). Engineered nucleases including CRISPR/Cas9 and transcription activator like effector nucleases (TALENs) provide powerful tools for enhancing gene...

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Bibliografische gegevens
Gepubliceerd in:Mol Ther
Hoofdauteurs: Smith, Cory, Abalde-Atristain, Leire, He, Chaoxia, Brodsky, Brett R, Braunstein, Evan M, Chaudhari, Pooja, Jang, Yoon-Young, Cheng, Linzhao, Ye, Zhaohui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351458/
https://ncbi.nlm.nih.gov/pubmed/25418680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.226
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