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Relationships among folate, alcohol consumption, gene variants in one-carbon metabolism and p16 (INK4a) methylation and expression in healthy breast tissues
p16 (INK4a) is a tumor suppressor gene, frequently hypermethylated in breast cancer; this epigenetic silencing of p16 (INK4a) occurs early in carcinogenesis. The risk factors and functional consequences of p16 (INK4a) methylation are unknown. Alcohol consumption, a breast cancer risk factor, impedes...
Zapisane w:
| Wydane w: | Carcinogenesis |
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| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351383/ https://ncbi.nlm.nih.gov/pubmed/25344837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu219 |
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