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Associations between genetic variation in one-carbon metabolism and LINE-1 DNA methylation in histologically normal breast tissues

Genome-wide DNA hypomethylation is an early event in the carcinogenic process. Percent methylation of long interspersed nucleotide element-1 (LINE-1) is a biomarker of genome-wide methylation and is a potential biomarker for breast cancer. Understanding factors associated with percent LINE-1 DNA met...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Llanos, Adana A M, Marian, Catalin, Brasky, Theodore M, Dumitrescu, Ramona G, Liu, Zhenhua, Mason, Joel B, Makambi, Kepher H, Spear, Scott L, Kallakury, Bhaskar V S, Freudenheim, Jo L, Shields, Peter G
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623023/
https://ncbi.nlm.nih.gov/pubmed/26090795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1062205
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