Detection of ROS1 Gene Rearrangement in Lung Adenocarcinoma: Comparison of IHC, FISH and Real-Time RT-PCR

AIMS: To compare fluorescence in situ hybridization (FISH), immunohistochemistry (IHC) and quantitative real-time reverse transcription-PCR (qRT-PCR) assays for detection of ROS1 fusion in a large number of ROS1-positive lung adenocatcinoma (ADC) patients. METHODS: Using IHC analysis, sixty lung ADC...

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Udgivet i:PLoS One
Main Authors: Shan, Ling, Lian, Fang, Guo, Lei, Qiu, Tian, Ling, Yun, Ying, Jianming, Lin, Dongmei
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351102/
https://ncbi.nlm.nih.gov/pubmed/25742289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120422
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