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Bora Downregulation Results in Radioresistance by Promoting Repair of Double Strand Breaks

Following DNA double-strand breaks cells activate several DNA-damage response protein kinases, which then trigger histone H2AX phosphorylation and the accumulation of proteins such as MDC1, p53-binding protein 1, and breast cancer gene 1 at the damage site to promote DNA double-strand breaks repair....

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Publicat a:PLoS One
Autors principals: Cairns, Junmei, Peng, Yi, Yee, Vivien C., Lou, Zhenkun, Wang, Liewei
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351037/
https://ncbi.nlm.nih.gov/pubmed/25742493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119208
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