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Distinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma

BACKGROUND: The mechanistic target of rapamycin, (mTOR) kinase plays a pivotal role in controlling critical cellular growth and survival pathways, and its aberrant induction is implicated in cancer pathogenesis. Therefore, suppression of active mTOR signaling has been of great interest to researcher...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Commun Signal
Main Authors: Mazan-Mamczarz, Krystyna, Peroutka, Raymond J, Steinhardt, James J, Gidoni, Moriah, Zhang, Yongqing, Lehrmann, Elin, Landon, Ari L, Dai, Bojie, Houng, Simone, Muniandy, Parameswary A, Efroni, Sol, Becker, Kevin G, Gartenhaus, Ronald B
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350884/
https://ncbi.nlm.nih.gov/pubmed/25849580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-015-0091-0
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