Distinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma

BACKGROUND: The mechanistic target of rapamycin, (mTOR) kinase plays a pivotal role in controlling critical cellular growth and survival pathways, and its aberrant induction is implicated in cancer pathogenesis. Therefore, suppression of active mTOR signaling has been of great interest to researcher...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Mazan-Mamczarz, Krystyna, Peroutka, Raymond J, Steinhardt, James J, Gidoni, Moriah, Zhang, Yongqing, Lehrmann, Elin, Landon, Ari L, Dai, Bojie, Houng, Simone, Muniandy, Parameswary A, Efroni, Sol, Becker, Kevin G, Gartenhaus, Ronald B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350884/
https://ncbi.nlm.nih.gov/pubmed/25849580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-015-0091-0
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