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Targeting Glutamatergic Signaling and the PI3 Kinase Pathway to Halt Melanoma Progression()()
Our group has previously reported that the majority of human melanomas (> 60%) express the metabotropic glutamate receptor 1 (GRM1) and that the glutamate release inhibitor riluzole, a drug currently used to treat amyotrophic lateral sclerosis, can induce apoptosis in GRM1-expressing melanoma cel...
Gespeichert in:
| Veröffentlicht in: | Transl Oncol |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Neoplasia Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4350641/ https://ncbi.nlm.nih.gov/pubmed/25749171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2014.11.001 |
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