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Glutamatergic Pathway Targeting in Melanoma; Single Agent and Combinatorial Therapies

PURPOSE: Melanoma is a heterogeneous disease where monotherapies are likely to fail due to variations in genomic signatures. B-RAF inhibitors have been clinically inadequate but response might be augmented with combination therapies targeting multiple signaling pathways. We investigate the pre-clini...

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Main Authors: Lee, Hwa Jin, Wall, Brian A., Wangari-Talbot, Janet, Shin, Seung-Shick, Rosenberg, Stephen, Chan, Joseph L.-K., Namkoong, Jin, Goydos, James S., Chen, Suzie
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218300/
https://ncbi.nlm.nih.gov/pubmed/21844014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0098
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