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Insights into copper coordination in the EcoRI–DNA complex by ESR spectroscopy
The EcoRI restriction endonuclease requires one divalent metal ion in each of two symmetrical and identical catalytic sites to catalyse double-strand DNA cleavage. Recently, we showed that Cu(2+) binds outside the catalytic sites to a pair of new sites at H114 in each sub-unit, and inhibits Mg(2+) -...
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| Publicado en: | Mol Phys |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4350447/ https://ncbi.nlm.nih.gov/pubmed/25750461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00268976.2014.934313 |
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