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Insights into copper coordination in the EcoRI–DNA complex by ESR spectroscopy
The EcoRI restriction endonuclease requires one divalent metal ion in each of two symmetrical and identical catalytic sites to catalyse double-strand DNA cleavage. Recently, we showed that Cu(2+) binds outside the catalytic sites to a pair of new sites at H114 in each sub-unit, and inhibits Mg(2+) -...
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| Publié dans: | Mol Phys |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4350447/ https://ncbi.nlm.nih.gov/pubmed/25750461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00268976.2014.934313 |
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