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Autoregulation of Inducible Nitric Oxide Synthase Expression by RNA Interference Provides Neuroprotection in Neonatal Rats

We have shown that autoregulation of gene expression by RNA interference is achievable in cell cultures. To determine whether this novel concept could be used to produce neuroprotection under in vivo condition, postnatal day (PND) 3 rats received intracerebroventricular injection of lentivirus that...

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Detalles Bibliográficos
Publicado en:Theranostics
Main Authors: Wang, Zhi, Feng, Chenzhuo, Zhao, Huijuan, Ren, Xiaoyan, Peng, Shuling, Zuo, Zhiyi
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350012/
https://ncbi.nlm.nih.gov/pubmed/25767617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.10441
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