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Autoregulation of Inducible Nitric Oxide Synthase Expression by RNA Interference Provides Neuroprotection in Neonatal Rats

We have shown that autoregulation of gene expression by RNA interference is achievable in cell cultures. To determine whether this novel concept could be used to produce neuroprotection under in vivo condition, postnatal day (PND) 3 rats received intracerebroventricular injection of lentivirus that...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Wang, Zhi, Feng, Chenzhuo, Zhao, Huijuan, Ren, Xiaoyan, Peng, Shuling, Zuo, Zhiyi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350012/
https://ncbi.nlm.nih.gov/pubmed/25767617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.10441
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