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Autoregulation of Inducible Nitric Oxide Synthase Expression by RNA Interference Provides Neuroprotection in Neonatal Rats

We have shown that autoregulation of gene expression by RNA interference is achievable in cell cultures. To determine whether this novel concept could be used to produce neuroprotection under in vivo condition, postnatal day (PND) 3 rats received intracerebroventricular injection of lentivirus that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Wang, Zhi, Feng, Chenzhuo, Zhao, Huijuan, Ren, Xiaoyan, Peng, Shuling, Zuo, Zhiyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350012/
https://ncbi.nlm.nih.gov/pubmed/25767617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.10441
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