Caspase-3-independent apoptotic pathways contribute to interleukin-32γ-mediated control of Mycobacterium tuberculosis infection in THP-1 cells

BACKGROUND: Macrophages are the primary effector cells responsible for killing Mycobacterium tuberculosis (MTB) through various mechanisms, including apoptosis. However, MTB can evade host immunity to create a favorable environment for intracellular replication. MTB-infected human macrophages produc...

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Pubblicato in:BMC Microbiol
Autori principali: Bai, Xiyuan, Kinney, William H, Su, Wen-Lin, Bai, An, Ovrutsky, Alida R, Honda, Jennifer R, Netea, Mihai G, Henao-Tamayo, Marcela, Ordway, Diane J, Dinarello, Charles A, Chan, Edward D
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349755/
https://ncbi.nlm.nih.gov/pubmed/25887904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-015-0366-z
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