Mycobacterium tuberculosis Induces Interleukin-32 Production through a Caspase- 1/IL-18/Interferon-γ-Dependent Mechanism

BACKGROUND: Interleukin (IL)–32 is a newly described proinflammatory cytokine that seems likely to play a role in inflammation and host defense. Little is known about the regulation of IL-32 production by primary cells of the immune system. METHODS AND FINDINGS: In the present study, freshly obtaine...

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Main Authors: Netea, Mihai G, Azam, Tania, Lewis, Eli C, Joosten, Leo A. B, Wang, Maorong, Langenberg, Dennis, Meng, Xianzhong, Chan, Edward D, Yoon, Do-Young, Ottenhoff, Tom, Kim, Soo-Hyun, Dinarello, Charles A
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539091/
https://ncbi.nlm.nih.gov/pubmed/16903774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030277
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