Intravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cells

The acquisition of cell motility is an early step in melanoma metastasis. Here we use intravital imaging of signalling reporter cell-lines combined with genome-wide transcriptional analysis to define signalling pathways and genes associated with melanoma metastasis. Intravital imaging revealed heter...

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Bibliographic Details
Published in:Oncogene
Main Authors: Manning, Cerys S, Hooper, Steven, Sahai, Erik A
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349503/
https://ncbi.nlm.nih.gov/pubmed/25381824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.362
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