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Apocalmodulin Itself Promotes Ion Channel Opening and Ca(2+) Regulation

The Ca(2+)-free form of calmodulin (apoCaM) often appears inert, modulating target molecules only upon conversion to its Ca(2+)-bound form. This schema has appeared to govern voltage-gated Ca(2+) channels, where apoCaM has been considered a dormant Ca(2+) sensor, associated with channels, but awaiti...

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Detalles Bibliográficos
Publicado en:Cell
Main Authors: Adams, Paul J., Ben-Johny, Manu, Dick, Ivy E., Inoue, Takanari, Yue, David T.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349394/
https://ncbi.nlm.nih.gov/pubmed/25417111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.047
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