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Mutation analysis of methylmalonyl CoA mutase gene exon 2 in Egyptian families: Identification of 25 novel allelic variants

Methylmalonic aciduria (MMA) is an autosomal recessive disorder of methylmalonate and cobalamin (cbl; vitamin B(12)) metabolism. It is an inborn error of organic acid metabolism which commonly results from a defect in the gene encoding the methylmalonyl-CoA mutase (MCM) apoenzyme. Here we report the...

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Pubblicato in:Meta Gene
Autori principali: Ghoraba, Dina A., Mohammed, Magdy M., Zaki, Osama K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349194/
https://ncbi.nlm.nih.gov/pubmed/25750861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mgene.2014.02.001
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