Radiation-Induced Lung Injury and Inflammation in Mice: Role of Inducible Nitric Oxide Synthase and Surfactant Protein D

Reactive nitrogen species (RNS) generated after exposure to radiation have been implicated in lung injury. Surfactant protein D (SP-D) is a pulmonary collectin that suppresses inducible nitric oxide synthase (iNOS)-mediated RNS production. Herein, we analyzed the role of iNOS and SP-D in radiation-i...

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Foilsithe in:Toxicol Sci
Main Authors: Malaviya, Rama, Gow, Andrew J., Francis, Mary, Abramova, Elena V., Laskin, Jeffrey D., Laskin, Debra L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2015
Ábhair:
Surfactant Protein D and iNOS in Radiation-Induced Lung Damage
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349136/
https://ncbi.nlm.nih.gov/pubmed/25552309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu255
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