Phase II Study of Everolimus and Letrozole in Patients With Recurrent Endometrial Carcinoma

PURPOSE: The phosphoinositol-3 kinase (PI3K) pathway is frequently dysregulated in endometrial cancer (EC). Hormonal manipulation leads to response in some patients with EC, but resistance derived from PI3K pathway activation has been documented. Targeting mammalian target of rapamycin (mTOR) may ov...

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Опубликовано в: :J Clin Oncol
Главные авторы: Slomovitz, Brian M., Jiang, Yunyun, Yates, Melinda S., Soliman, Pamela T., Johnston, Taren, Nowakowski, Maureen, Levenback, Charles, Zhang, Qian, Ring, Kari, Munsell, Mark F., Gershenson, David M., Lu, Karen H., Coleman, Robert L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Clinical Oncology 2015
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ORIGINAL REPORTS
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348638/
https://ncbi.nlm.nih.gov/pubmed/25624430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.58.3401
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