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Phase II Study of Everolimus and Letrozole in Patients With Recurrent Endometrial Carcinoma

PURPOSE: The phosphoinositol-3 kinase (PI3K) pathway is frequently dysregulated in endometrial cancer (EC). Hormonal manipulation leads to response in some patients with EC, but resistance derived from PI3K pathway activation has been documented. Targeting mammalian target of rapamycin (mTOR) may ov...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Slomovitz, Brian M., Jiang, Yunyun, Yates, Melinda S., Soliman, Pamela T., Johnston, Taren, Nowakowski, Maureen, Levenback, Charles, Zhang, Qian, Ring, Kari, Munsell, Mark F., Gershenson, David M., Lu, Karen H., Coleman, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348638/
https://ncbi.nlm.nih.gov/pubmed/25624430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.58.3401
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