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Phase II Study of Everolimus and Letrozole in Patients With Recurrent Endometrial Carcinoma
PURPOSE: The phosphoinositol-3 kinase (PI3K) pathway is frequently dysregulated in endometrial cancer (EC). Hormonal manipulation leads to response in some patients with EC, but resistance derived from PI3K pathway activation has been documented. Targeting mammalian target of rapamycin (mTOR) may ov...
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Publicado no: | J Clin Oncol |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Clinical Oncology
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4348638/ https://ncbi.nlm.nih.gov/pubmed/25624430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.58.3401 |
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