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Crystal structure of human angiogenin reveals the structural basis for its functional divergence from ribonuclease.

Angiogenin, a potent inducer of neovascularization, is the only angiogenic molecule known to exhibit ribonucleolytic activity. Its overall structure, as determined at 2.4 A, is similar to that of pancreatic ribonuclease A, but it differs markedly in several distinct areas, particularly the ribonucle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Acharya, K R, Shapiro, R, Allen, S C, Riordan, J F, Vallee, B L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC43485/
https://ncbi.nlm.nih.gov/pubmed/8159679
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