Sphingosine-1-Phosphate Mediates ICAM-1-Dependent Monocyte Adhesion through p38 MAPK and p42/p44 MAPK-Dependent Akt Activation

Up-regulation of intercellular adhesion molecule-1 (ICAM-1) is frequently implicated in lung inflammation. Sphingosine-1-phosphate (S1P) has been shown to play a key role in inflammation via adhesion molecules induction, and then causes lung injury. However, the mechanisms underlying S1P-induced ICA...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lin, Chih-Chung, Lee, I-Ta, Hsu, Chun-Hao, Hsu, Chih-Kai, Chi, Pei-Ling, Hsiao, Li-Der, Yang, Chuen-Mao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348486/
https://ncbi.nlm.nih.gov/pubmed/25734900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118473
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