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Quantification of [(11)C]yohimbine binding to α(2) adrenoceptors in rat brain in vivo

We quantified the binding potentials (BP(ND)) of [(11)C]yohimbine binding in rat brain to alpha-2 adrenoceptors to evaluate [(11)C]yohimbine as an in vivo marker of noradrenergic neurotransmission and to examine its sensitivity to the level of noradrenaline. Dual [(11)C]yohimbine dynamic positron em...

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Dades bibliogràfiques
Publicat a:J Cereb Blood Flow Metab
Autors principals: Phan, Jenny-Ann, Landau, Anne M, Wong, Dean F, Jakobsen, Steen, Nahimi, Adjmal, Doudet, Doris J, Gjedde, Albert
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348393/
https://ncbi.nlm.nih.gov/pubmed/25564241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.225
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