Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation

Pro-inflammatory cytokine-induced activation of nuclear factor, NF-κB has an important role in leukocyte adhesion to, and subsequent migration across, brain endothelial cells (BECs), which is crucial for the development of neuroinflammatory disorders such as multiple sclerosis (MS). In contrast, mic...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Wu, Dongsheng, Cerutti, Camilla, Lopez-Ramirez, Miguel A, Pryce, Gareth, King-Robson, Josh, Simpson, Julie E, van der Pol, Susanne MA, Hirst, Mark C, de Vries, Helga E, Sharrack, Basil, Baker, David, Male, David K, Michael, Gregory J, Romero, Ignacio A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348377/
https://ncbi.nlm.nih.gov/pubmed/25515214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.207
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