Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation

Pro-inflammatory cytokine-induced activation of nuclear factor, NF-κB has an important role in leukocyte adhesion to, and subsequent migration across, brain endothelial cells (BECs), which is crucial for the development of neuroinflammatory disorders such as multiple sclerosis (MS). In contrast, mic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cereb Blood Flow Metab
Prif Awduron: Wu, Dongsheng, Cerutti, Camilla, Lopez-Ramirez, Miguel A, Pryce, Gareth, King-Robson, Josh, Simpson, Julie E, van der Pol, Susanne MA, Hirst, Mark C, de Vries, Helga E, Sharrack, Basil, Baker, David, Male, David K, Michael, Gregory J, Romero, Ignacio A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348377/
https://ncbi.nlm.nih.gov/pubmed/25515214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.207
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