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Impaired Attention and Synaptic Senescence of the Prefrontal Cortex Involves Redox Regulation of NMDA Receptors

Young (3–6 months) and middle-age (10–14 months) rats were trained on the five-choice serial reaction time task. Attention and executive function deficits were apparent in middle-age animals observed as a decrease in choice accuracy, increase in omissions, and increased response latency. The behavio...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Guidi, Michael, Kumar, Ashok, Foster, Thomas C.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348191/
https://ncbi.nlm.nih.gov/pubmed/25740525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3523-14.2015
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