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A Novel, Ultrasensitive Assay for Tau: Potential for Assessing Traumatic Brain Injury in Tissues and Biofluids

Traumatic brain injury (TBI) is a cause of death and disability and can lead to tauopathy-related dementia at an early age. Pathologically, TBI results in axonal injury that is coupled to tau hyperphosphorylation, leading to microtubule instability and tau-mediated neurodegeneration. This suggests t...

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Detalhes bibliográficos
Publicado no:J Neurotrauma
Main Authors: Rubenstein, Richard, Chang, Binggong, Davies, Peter, Wagner, Amy K., Robertson, Claudia S., Wang, Kevin K.W.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348038/
https://ncbi.nlm.nih.gov/pubmed/25177776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2014.3548
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