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Up-Regulation of Programmed Death-1 Expression on Beryllium-Specific CD4(+) T Cells in Chronic Beryllium Disease()

Chronic beryllium disease (CBD) is caused by workplace exposure to beryllium and is characterized by the accumulation of memory CD4(+) T cells in the lung. These cells respond vigorously to beryllium salts in culture by producing proinflammatory Th1-type cytokines. The presence of these inflammatory...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Palmer, Brent E., Mack, Douglas G., Martin, Allison K., Gillespie, May, Mroz, Margaret M., Maier, Lisa A., Fontenot, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347847/
https://ncbi.nlm.nih.gov/pubmed/18250483
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