Deficient and Dysfunctional Regulatory T Cells in the Lungs of Chronic Beryllium Disease Subjects

Rationale: Chronic beryllium disease (CBD) is a CD4(+) T cell–mediated disorder characterized by persistent lung inflammation. Naturally occurring regulatory T (T(reg)) cells modulate adaptive immune responses. The role of this T-cell subset in beryllium-induced lung disease is unknown. Objectives:...

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Detalhes bibliográficos
Main Authors: Mack, Douglas G., Lanham, Allison M., Falta, Michael T., Palmer, Brent E., Maier, Lisa A., Fontenot, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
C. Environmental and Occupational Lung Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891494/
https://ncbi.nlm.nih.gov/pubmed/20299529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201001-0025OC
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