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Stemness factor Sall4 is required for DNA damage response in embryonic stem cells

Mouse embryonic stem cells (ESCs) are genetically more stable than somatic cells, thereby preventing the passage of genomic abnormalities to their derivatives including germ cells. The underlying mechanisms, however, remain largely unclear. In this paper, we show that the stemness factor Sall4 is re...

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Bibliografische gegevens
Gepubliceerd in:J Cell Biol
Hoofdauteurs: Xiong, Jianhua, Todorova, Dilyana, Su, Ning-Yuan, Kim, Jinchul, Lee, Pei-Jen, Shen, Zhouxin, Briggs, Steven P., Xu, Yang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347641/
https://ncbi.nlm.nih.gov/pubmed/25733712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408106
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