Stemness factor Sall4 is required for DNA damage response in embryonic stem cells

Mouse embryonic stem cells (ESCs) are genetically more stable than somatic cells, thereby preventing the passage of genomic abnormalities to their derivatives including germ cells. The underlying mechanisms, however, remain largely unclear. In this paper, we show that the stemness factor Sall4 is re...

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Udgivet i:J Cell Biol
Main Authors: Xiong, Jianhua, Todorova, Dilyana, Su, Ning-Yuan, Kim, Jinchul, Lee, Pei-Jen, Shen, Zhouxin, Briggs, Steven P., Xu, Yang
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347641/
https://ncbi.nlm.nih.gov/pubmed/25733712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408106
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