Filamin A interaction with the CXCR4 third intracellular loop regulates endocytosis and signaling of WT and WHIM-like receptors

Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is a rare congenital immunodeficiency often caused by mutations in the last 10 to 19 C-terminal amino acids of CXCR4. These mutations impair CXCR4 internalization and increase responsiveness to CXCL12. The CXCR4 C-terminal d...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Blood
Hoofdauteurs: Gómez-Moutón, Concepción, Fischer, Thierry, Peregil, Rosa M., Jiménez-Baranda, Sonia, Stossel, Thomas P., Nakamura, Fumihiko, Mañes, Santos
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2015
Onderwerpen:
Immunobiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347305/
https://ncbi.nlm.nih.gov/pubmed/25355818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-601807
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items