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Documentation and Localization of Force-mediated Filamin A Domain Perturbations in Moving Cells

Endogenously and externally generated mechanical forces influence diverse cellular activities, a phenomenon defined as mechanotransduction. Deformation of protein domains by application of stress, previously documented to alter macromolecular interactions in vitro, could mediate these effects. We en...

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Detalhes bibliográficos
Main Authors: Nakamura, Fumihiko, Song, Mia, Hartwig, John H., Stossel, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139033/
https://ncbi.nlm.nih.gov/pubmed/25120197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5656
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