Structural basis of filamin A functions

Filamin A (FLNa) can effect orthogonal branching of F-actin and bind many cellular constituents. FLNa dimeric subunits have N-terminal spectrin family F-actin binding domains (ABDs) and an elongated flexible segment of 24 immunoglobulin (Ig) repeats. We generated a library of FLNa fragments to exami...

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Detalhes bibliográficos
Main Authors: Nakamura, Fumihiko, Osborn, Teresia M., Hartemink, Christopher A., Hartwig, John H., Stossel, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099194/
https://ncbi.nlm.nih.gov/pubmed/18056414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707073
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