GM-CSF–dependent pSTAT5 sensitivity is a feature with therapeutic potential in chronic myelomonocytic leukemia

Granulocyte-macrophage–colony-stimulating factor (GM-CSF) hypersensitivity is a hallmark of juvenile myelomonocytic leukemia (JMML) but has not been systematically shown in the related human disease chronic myelomonocytic leukemia (CMML). We find that primary CMML samples demonstrate GM-CSF–dependen...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Padron, Eric, Painter, Jeffrey S., Kunigal, Sateesh, Mailloux, Adam W., McGraw, Kathy, McDaniel, Jessica M., Kim, Eunhee, Bebbington, Christopher, Baer, Mark, Yarranton, Geoffrey, Lancet, Jeffrey, Komrokji, Rami S., Abdel-Wahab, Omar, List, Alan F., Epling-Burnette, Pearlie K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347259/
https://ncbi.nlm.nih.gov/pubmed/23632888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-460170
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