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Cytokine therapy reverses NK cell anergy in MHC-deficient tumors
Various cytokines have been evaluated as potential anticancer drugs; however, most cytokine trials have shown relatively low efficacy. Here, we found that treatments with IL-12 and IL-18 or with a mutant form of IL-2 (the “superkine” called H9) provided substantial therapeutic benefit for mice speci...
Gardado en:
| Publicado en: | J Clin Invest |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347250/ https://ncbi.nlm.nih.gov/pubmed/25329698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74337 |
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