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Axonally derived matrilin-2 induces proinflammatory responses that exacerbate autoimmune neuroinflammation
In patients with multiple sclerosis (MS) and mice with experimental autoimmune encephalomyelitis (EAE), inflammatory axonal injury is a major determinant of disability; however, the drivers of this injury are incompletely understood. Here, we used the EAE model and determined that the extracellular...
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Publicado no: | J Clin Invest |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347228/ https://ncbi.nlm.nih.gov/pubmed/25329699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71385 |
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