Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome

Excessive activation of the NLRP3 inflammasome results in damaging inflammation, yet the regulators of this process remain poorly defined. Herein, we show that the orphan nuclear receptor small heterodimer partner (SHP) is a negative regulator of NLRP3 inflammasome activation. NLRP3 inflammasome act...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yang, Chul-Su, Kim, Jwa-Jin, Kim, Tae Sung, Lee, Phil Young, Kim, Soo Yeon, Lee, Hye-Mi, Shin, Dong-Min, Nguyen, Loi T., Lee, Moo-Seung, Jin, Hyo Sun, Kim, Kwang-Kyu, Lee, Chul-Ho, Kim, Myung Hee, Park, Sung Goo, Kim, Jin-Man, Choi, Hueng-Sik, Jo, Eun-Kyeong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347017/
https://ncbi.nlm.nih.gov/pubmed/25655831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7115
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados