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Oxidative Stress, Bone Marrow Failure, and Genome Instability in Hematopoietic Stem Cells

Reactive oxygen species (ROS) can be generated by defective endogenous reduction of oxygen by cellular enzymes or in the mitochondrial respiratory pathway, as well as by exogenous exposure to UV or environmental damaging agents. Regulation of intracellular ROS levels is critical since increases abov...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Richardson, Christine, Yan, Shan, Vestal, C. Greer
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346841/
https://ncbi.nlm.nih.gov/pubmed/25622253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16022366
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