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Oxidative Stress, Bone Marrow Failure, and Genome Instability in Hematopoietic Stem Cells

Reactive oxygen species (ROS) can be generated by defective endogenous reduction of oxygen by cellular enzymes or in the mitochondrial respiratory pathway, as well as by exogenous exposure to UV or environmental damaging agents. Regulation of intracellular ROS levels is critical since increases abov...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Richardson, Christine, Yan, Shan, Vestal, C. Greer
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346841/
https://ncbi.nlm.nih.gov/pubmed/25622253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16022366
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