Lung matrix and vascular remodeling in mechanically ventilated elastin haploinsufficient newborn mice

Elastin plays a pivotal role in lung development. We therefore queried if elastin haploinsufficient newborn mice (Eln(+/−)) would exhibit abnormal lung structure and function related to modified extracellular matrix (ECM) composition. Because mechanical ventilation (MV) has been linked to dysregulat...

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Gepubliceerd in:Am J Physiol Lung Cell Mol Physiol
Hoofdauteurs: Hilgendorff, Anne, Parai, Kakoli, Ertsey, Robert, Navarro, Edwin, Jain, Noopur, Carandang, Francis, Peterson, Joanna, Mokres, Lucia, Milla, Carlos, Preuss, Stefanie, Alcazar, Miguel Alejandre, Khan, Suleman, Masumi, Juliet, Ferreira-Tojais, Nancy, Mujahid, Sana, Starcher, Barry, Rabinovitch, Marlene, Bland, Richard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346771/
https://ncbi.nlm.nih.gov/pubmed/25539853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00278.2014
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