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Potential Small Guide RNAs for tRNase Z(L) from Human Plasma, Peripheral Blood Mononuclear Cells, and Cultured Cell Lines

Several pieces of evidence suggest that small RNA degradation products together with tRNase Z(L) appear to form another layer of the whole gene regulatory network. The degraded RNA such as a 5′-half-tRNA and an rRNA fragment function as small guide RNA (sgRNA) to guide the enzyme to target RNA. We w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ninomiya, Sho, Kawano, Mitsuoki, Abe, Takashi, Ishikawa, Tatsuya, Takahashi, Masayuki, Tamura, Masato, Takahashi, Yoshiaki, Nashimoto, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346264/
https://ncbi.nlm.nih.gov/pubmed/25730316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118631
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