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Synthesis and structure activity relationship studies of novel Staphylococcus aureus Sortase A inhibitors
Synthetic methods have been developed for the lead Sortase A inhibitors identified from previous studies. Several derivatives of the lead inhibitor were synthesized to derive preliminary structure activity relationships (SAR). Different regions of the lead inhibitor that are critical for the enzyme...
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| Pubblicato in: | Eur J Med Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4346195/ https://ncbi.nlm.nih.gov/pubmed/20541848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2010.05.024 |
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