Chargement en cours...
Analogs of the marine alkaloid makaluvamines: Synthesis, topoisomerase II inhibition and anticancer activity
Twelve analogs of makaluvamines have been synthesized. These compounds were evaluated for their ability to inhibit the enzyme topoisomerase II. Five compounds were shown to inhibit topoisomerase catalytic activity comparable to two known topoisomerase II targeting control drugs, etoposide and m-AMSA...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706148/ https://ncbi.nlm.nih.gov/pubmed/17368022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.02.065 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|