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Thermodynamic mechanism for inhibition of lactose permease by the phosphotransferase protein IIA(Glc)

In a variety of bacteria, the phosphotransferase protein IIA(Glc) plays a key regulatory role in catabolite repression in addition to its role in the vectorial phosphorylation of glucose catalyzed by the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). The lactose permease (LacY) of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hariharan, Parameswaran, Balasubramaniam, Dhandayuthapani, Peterkofsky, Alan, Kaback, H. Ronald, Guan, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345578/
https://ncbi.nlm.nih.gov/pubmed/25675534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1500891112
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