Ligand-directed targeting of lymphatic vessels uncovers mechanistic insights in melanoma metastasis

Metastasis is the most lethal step of cancer progression in patients with invasive melanoma. In most human cancers, including melanoma, tumor dissemination through the lymphatic vasculature provides a major route for tumor metastasis. Unfortunately, molecular mechanisms that facilitate interactions...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Christianson, Dawn R., Dobroff, Andrey S., Proneth, Bettina, Zurita, Amado J., Salameh, Ahmad, Dondossola, Eleonora, Makino, Jun, Bologa, Cristian G., Smith, Tracey L., Yao, Virginia J., Calderone, Tiffany L., O'Connell, David J., Oprea, Tudor I., Kataoka, Kazunori, Cahill, Dolores J., Gershenwald, Jeffrey E., Sidman, Richard L., Arap, Wadih, Pasqualini, Renata
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2015
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345577/
https://ncbi.nlm.nih.gov/pubmed/25659743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424994112
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